PermaNet 2.0

Product Description

PermaNet 2.0: A long-lasting insecticidal net (LLIN) composed of knitted poly-filament polyester fibers and infused with deltamethrin to knockdown and kill mosquitos that come in contact with it.

Target SDGs

SDG 3: Good Health and Well-Being

Target Users (Target Impact Group)

Household, Community

Distributors / Implementing Organizations

Vestergaard Frandsen works with local partners in country to deliver products to end users.

Competitive Landscape

Direct competitors include Olyset Net and Interceptor.

Manufacturing/Building Method

Mass manufactured

Intellectural Property Type

Patent

User Provision Model

Vestergaard Frandsen has developed a distribution network across Africa with the help of local partners that helps deliver the product through direct sales.

Distributions to Date Status

Millions are distributed each year.

Bursting Strength (kPa)

> 250

Denier

75 – 100

Expected lifespan (months, washes)

30, unknown

Insecticide content (g/kg)

1.4 – 1.8 + 25%

Insecticide(s) used

Deltamethrin

Mesh (holes/cm^2)

Protection from insect entry (yes/no)

Yes.

Retreatment required? (frequency)

No.

Design Specifications

The net is made from knitted poly-filament polyester fibers.

Product Schematics

Technical Support

After a certain period of use, Vestergaard Frandsen Hanoi laboratories offers testing to ensure proper functionality of the nets.

Replacement Components

Holes can be patched with local materials, although the insecticide will no longer be present on that spot.

Lifecycle

Lifetime largely depends on usage.

Manufacturer Specified Performance Parameters

Targets:

Less than 5% shrinkage/expansion in both dimensions
Rapidly regains insecticidal efficacy after washing

Vetted Performance Status

Report of the Twelfth WHOPES Working Group Meeting: More than 90% of nets tested at each time-point met the WHOPES criteria for the cone test, except for nets collected at 24 months post-distribution, when only 71% of nets met the WHOPES criteria for the cone test.

1.4 g/kg deltamethrin concentration for 100-denier net
1.8 g/kg deltamethrin concentration for 75-denier net
41.5% retention of deltamethrin concentration after 36 months

*more than half of nets tested had holes by 3-6 months of use (and 92.5% by 26-32 months)

Safety

Unknown

Complementary Technical Systems

None

Academic Research and References

Wills, A.B., et al., Physical durability of PermaNet 2.0 long-lasting insecticidal nets over three to 32 months of use in Ethiopia. Malaria Journal. 2013 Jul 15;12(242):1-13.

Koudou, B.G., Koffi, A.A., Malone, D., Hemingway, J., Efficacy of PermaNet 2.0 and PermaNet 3.0 against insecticide-resistant Anopheles gambiae in experimental huts in Cote d’Ivoire. Malaris Journal. 2011;10(172):1-10.

Sreehari, U., et al., Efficacy of PermaNet 2.0 against Anopheles culicifacies, and Anopheles stephensi, malaria vectors in India. Journal of the American Mosquito Control Association. 2007;23(2):220-223.

Picado, A., Residual activity and integrity of PermaNet® 2.0 after 24 months of household use in a community randomised trial of long lasting insecticidal nets against visceral leishmaniasis in India and Nepal. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2012 Mar;106(3):150-159.

Prakash, A., et al., Evaluation of PermaNet 2.0 mosquito bednets against mosquitoes, including Anopheles minimus s.l., in India. The Southeast Asian Journal of Tropical Medicine and Public Health. 2009 May;40(3):449-457.

Vestergaard. “PermaNet 2.0.” Vestergaard, 2023.

World Health Organization. “REPORT OF THE TWELFTH WHOPES WORKING GROUP MEETING.” World Health Organization, 2008.

Compliance with regulations

One published study on Phase III evaluation of the nets as per WHOPES standards. PermaNet®2.0 satisfies the WHO specification 333/LN

Evaluation methods

Reports of randomized household trials and cross-sectional surveys in six different African countries, including efficacy and durability information gathering. Bioassay and Chemical assay testing of about 1,000 nets. Extensive reporting of test results available on WHOPES document.